Thom Tillis (R-NC), likely Senate Republican’s most vulnerable member to a Democratic challenger in 2026, and Sen. Rand Paul (R-KY) voted against the motion. Vice President JD Vance was on hand to brake a tie,

“We have been successful in removing parts of this bill that hurt families and workers, but the process is not over, and Democrats are continuing to make the case against every provision in this Big, Beautiful Betrayal of a bill that violates Senate rules,” Ranking Member Jeff Merkley (D-Ore.) said in a statement.

'One Big Beautiful Bill' clears 1st procedural hurdle 51-49 after dramatic vote that lasted almost 4 hours The Senate voted to advance the "One Big Beautiful Bill," kicking off a lengthy process that GOP leadership hopes will end in its final passage.