The New York Yankees (24-18) visit the Seattle Mariners (23-18) in the third and final game of their 3-game series on Wednesday. First pitch from T-Mobile Park is at 4:10 p.m. ET (MLB Network). Let's analyze BetMGM Sportsbook's MLB odds around the Yankees vs. Mariners odds and make our expert MLB picks and predictions for the best bets.

The Seattle Mariners entered Tuesday on a four-game losing streak and in crucial need of momentum. J.P. Crawford snapped the skid and gave the Mariners the much-needed win with an 11th-inning, walk-off single down the New York Yankees 2-1.

Our MLB betting picks believe the Yankees have the advantage in this matchup with Luis Castillo at T-Mobile Park, and will gladly fade the Mariners at generous odds on Wednesday, May 14, 2025.