In 3D cell culture, rather than growing as a layer, cells are cultured in a three-dimensional shape in a gel matrix, or in the form of spheroids or organoids. 3D cultures can be used as model systems ...

Integrated protocols and live-cell analysis solutions for different 3D tumor models In the search for greater clinical translation, cancer researchers are increasingly turning to more complex ...

The researchers designed their model system using clumps of cervical cancer cells in simple 3D tissues that they could control, enabling them to systematically study the behaviour of the cells in ...

In fact, over 90 percent of drug candidates that show promise in preclinical studies ultimately fail in clinical trials, largely due to the limitations of traditional models. 3D cell culture provides ...

A new application of artificial intelligence could help researchers solve medical mysteries ranging from cancer to Alzheimer's. It's a 3D model of a living human cell that lets scientists study ...

We will demonstrate the suitability of these cell health microplate assays to examine differential responses of investigational compounds in 2D (monolayers) versus 3D (spheroids) models. These ...

An easy-to-use model. Lead author of the study, Juliana Gutschow Gameiro, a former Ph.D. student visiting GSBS, came to Tufts from the State University of Londrina, Parana, in Brazil.

The model is easy and affordable to replicate, ... Brian Lin. Quiescent horizontal basal stem cells act as a niche for olfactory neurogenesis in a mouse 3D organoid model. Cell Reports Methods, ...

As researchers explore therapeutic strategies for more complex and heterogeneous diseases the need for more physiologically relevant models has never been greater. Researchers are increasingly looking ...