A simulation study demonstrated the adequacy of our formulas in finite sample size settings. An application to a clinical trial to evaluate the treatment effect on prevention of COPD exacerbation is ...

Comparing results of a single-arm early-phase trial to those of a rigorously matched HCT ECA yielded insights regarding comparative efficacy prior to a randomized controlled trial. The effect size ...

Preimplantation genetic testing in fertility treatment can detect chromosomal abnormalities in embryos leading to higher live birth rates in IVF.

Ivermectin to Control Malaria — A Cluster-Randomized Trial Results A total of 84 clusters comprising 28,932 eligible participants underwent randomization.

We conducted this phase 2b, randomized, double-blind, placebo-controlled trial at 61 sites in the United States to evaluate the efficacy and safety of pegozafermin over a treatment period of 24 weeks.