A simulation study demonstrated the adequacy of our formulas in finite sample size settings. An application to a clinical trial to evaluate the treatment effect on prevention of COPD exacerbation is ...

Comparing results of a single-arm early-phase trial to those of a rigorously matched HCT ECA yielded insights regarding comparative efficacy prior to a randomized controlled trial. The effect size ...

A sample size of 160 individuals (80 to each study arm) for this trial was determined on the basis of the F -test to detect a time by treatment group interaction effect at the 5% significance level ...

We conducted this phase 2b, randomized, double-blind, placebo-controlled trial at 61 sites in the United States to evaluate the efficacy and safety of pegozafermin over a treatment period of 24 weeks.

Ivermectin to Control Malaria — A Cluster-Randomized Trial Results A total of 84 clusters comprising 28,932 eligible participants underwent randomization.

Preimplantation genetic testing in fertility treatment can detect chromosomal abnormalities in embryos leading to higher live birth rates in IVF.