Classical regression analysis is usually performed in two steps. In a first step an appropriate model is identified to describe the data-generating process and in a second step statistical inference ...

The customary approach to early-phase clinical trial design, where the focus is on identification of the maximum tolerated dose, is not always suitable for noncytotoxic or other targeted therapies.

This paper proposes a practical and efficient method for the development of visual interactive meta-simulation models using neural networks. The method first uses a randomised simulation experimental ...