Objective Hepatic stellate cells (HSC) transdifferentiation into myofibroblasts is central to fibrogenesis. Epigenetic mechanisms, including histone and DNA methylation, play a key role in this ...

Division of Hepatology and Metabolism, Department of Internal Medicine, Saga Medical School, Saga, Japan Dr I Ozaki, Division of Hepatology and Metabolism, Department of Internal Medicine, Saga ...

1 Dalhousie Inflammation Group and Department of Pediatrics, and Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada 2 Dalhousie Inflammation Group and ...

Objective To appraise the evidence that pathophysiological mechanisms and individualised treatment directed at those mechanisms provide an alternative approach to the treatment of patients with ...

Correspondence to Dr Barham K Abu Dayyeh, Clinical Enteric Neuroscience Translational and Epidemiological Research (C.E.N.T.E.R), Division of Gastroenterology and Hepatology, Mayo Clinic Rochester, ...

1 Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Greenebaum Cancer Center, Baltimore, Maryland, USA 2 Division of Gastroenterology and Hepatology, ...

2 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham General Hospital, Cheltenham, UK 3 Department of Gastroenterology, Gloucestershire Hospitals NHS Foundation ...

Cholelithiasis among male and female patients at the Royal Melbourne Hospital was studied, and the incidence of the disease in relation to various clinical and dietary factors is discussed. The ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...

Dr V V Smith, Histopathology, Camelia Botnar Laboratories, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK. Three infants, who presented with intestinal obstruction due to ...

1 Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark 2 Center for Sensory-Motor Interactions, Department of Health Science and Technology, Aalborg University, ...

Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly of gut microbial origin, as deduced from studies in animals. The aim of the study is to characterise ...