aDivision of Metabolism, Digestion and Reproduction, Imperial College London, London, UK bDepartment of Diabetes and Endocrinology, Imperial College Healthcare NHS Trust, London, UK cDepartment of ...

Research discoveries leading to the development of new pharmaceutical compounds are notoriously difficult to translate into clinical practice.1 Drug repurposing provides a strategy to identify ...

We write to highlight an urgent, yet preventable public health tragedy unfolding in the Ecuadorian Amazon. In May, 2025, eight Indigenous Achuar children from Taisha—an Amazonic village from the ...

The current mpox outbreak in Sierra Leone is the largest ever recorded in the country and the first major epidemic caused by the clade IIb monkeypox virus in Africa. Since a public health emergency ...

In a single frame a photograph is a powerful way to tell a story and highlight an important issue. Each year The Lancet invites submissions for the Highlights photography competition and since 2009 we ...

Hybrid closed-loop insulin delivery systems are transforming the management of type 1 diabetes. Young children with type 1 ...

Obstructive sleep apnoea (OSA) is an important condition,1 but its role as a reversible cardiovascular risk factor has been ...

Michelle Monje is the Milan Gambhir Professor of Pediatric Neuro-Oncology at Stanford University, CA, USA, and a Howard ...

Lindgren and colleagues reported alarming health disparities in the Ten Americas study,1 which grouped populations based on race, ethnicity, and various geographical and sociodemographic factors. The ...

The adoption of the WHO Pandemic Agreement marks a pivotal moment in global health governance,1 particularly through the inclusion of the One Health approach. This holistic approach, integrating human ...

One small city's bid to rescue its health finances has transformed the way health care is managed across China. Chris McCall ...

Life, as philosopher Søren Kierkegaard put it, “must be understood backwards; but…it must be lived forwards”.1 Clinical ...