Bills beat Colts for fifth straight win, improve to 8-2 for first time since 1993 (full coverage) Buffalo Bills ...

The Buffalo Bills’ matchup against the Indianapolis Colts proved to be an ugly turnover fest on Sunday, mostly for Joe Flacco ...

The NFL is often a war of attrition, and Week 10 has been no exception. Here, we're keeping track of all the notable injuries ...

T he Indianapolis Colts are not favored in their matchup against the Buffalo Bills. Most people wouldn’t expect them to be.

Buffalo Bills running back James Cook flips into the end zone against the Indianapolis Colts for his eighth rushing touchdown of the season.

The Bills had not won in Indianapolis since 1998, losing their last six combined at the old RCA Dome and Lucas Oil Stadium.

Off-platform dime! Buffalo Bills quarterback Josh Allen's improv lob to wide receiver Mack Hollins goes for a 44-yard gain ...

Taron Johnson returned Joe Flacco’s first pass 23 yards for a touchdown, and Josh Allen and James Cook each scored on TD runs ...

Indianapolis Colts quarterback Joe Flacco's struggles were on full display during a 30-20 loss to the Buffalo Bills on Sunday ...

Buf_Ta.Johnson 23 interception return (Bass kick), 12:14. Buffalo 7, Indianapolis 0. Buf_FG Bass 29, 5:33. Drive: 9 plays, 42 yards, 3:33. Key Plays: Au.Johnson 4 interception return to Buffalo 47; ...

How to watch Giants vs Panthers, Broncos vs Chiefs, 49ers vs Buccaneers, Eagles vs Cowboys, Lions vs Texans, more NFL Week 10 ...

The Denver Broncos were a field goal away from handing the Kansas City Chiefs their first loss of the season Sunday afternoon ...