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In 1938, a Swiss chemist working with compounds derived from ergot, a fungus found on rye, synthesized a molecule that seemed unremarkable and was set aside. For years, it sat untouched, buried among other experiments that showed little promise. Then in April 1943, something drew him back to it, as if the work wasn’t finished. While handling the substance again, a tiny amount was accidentally absorbed, leading to a sudden and unusual shift in perception. Intrigued by what he felt, he decided to
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