A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

HHMI researchers have discovered that a specific type of calcium channel—a pore-like protein that is nestled in the cell membrane and controls the flow of calcium into the cell—regulates the ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...