Your complement system consists of a group of important proteins in your bloodstream. These proteins help your immune system fight off harmful invaders, such as bacteria, and other foreign substances.

Studies of monogenic gastrointestinal diseases have revealed molecular pathways critical to gut homeostasis and enabled the development of targeted therapies. We studied 11 patients with abdominal ...

Here, we describe a patient with an early onset of endocapillary glomerulonephritis and CFH deficiency. Genetic analyses revealed uniparental isodisomy and a novel mutation as the unusual molecular ...