Innate immunity is a foundational field in immunology, critical for understanding how organisms sense and respond to danger, be it pathogens or sterile ...

Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite ...

The complement component C5a and its receptors, C5aR1 and C5aR2, are central to the orchestration of innate immunity. C5a is a potent anaphylatoxin generated during complement activation, acting as a ...

Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function. The advent of severe acute ...

Immunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. While much focus has been on engaging T-cells for fighting cancer, less attention has been ...

This article was published in Scientific American’s former blog network and reflects the views of the author, not necessarily those of Scientific American The very first line of defence against any ...

Dianthus Therapeutics Inc. has, appropriately, flowered in springtime. The Waltham, Mass.-based company emerged from stealth with $100 million in series A funding and lofty ambitions to rewrite the ...

Oncolytic virus immunotherapy has been proposed as a step forward for cancer treatment because it can kill cancer cells while activating the immune system. However, its current clinical application is ...

This is part of a series of stories on the protective role of innate lymphoid cells (ILCs) in the gut and other tissues, focusing on SARS-CoV-2 infection. One area that hasn’t received all that much ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...