Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...

Research from Radboud university medical center reveals that T cells from the adaptive immune system can manipulate the memory of innate immune cells. Previously, it was believed that the memory of ...

SARS-CoV-2 has an enzyme that can counteract a cell's innate defense mechanism against viruses, explaining why it is more infectious than the previous SARS and MERS-causing viruses. The discovery may ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

Dianthus achieved its NASDAQ listing last year via a merger with Magenta Therapeutics. The company is focused on development of a single drug candidate, DNTH-103, which targets the complement system, ...

Antibodies, which recognize viruses and proteins that the body has encountered before, have long gotten most of the credit for giving the human immune system a memory. Now, researchers at the ...

During the recent Covid-19 pandemic, the rate of serious illness and death was jarringly high in older populations. Why? Weakening immune systems — as we age, we become more vulnerable to infections, ...

Researchers have shown that innate immune training, also known as trained immunity (TRIM), leads to aggravated bone loss in experimental models of periodontitis and inflammatory arthritis. Clinical ...

Antimicrobial resistance (AMR) poses one of the greatest threats to global public health, with excessive antibiotic use driving the emergence of ...