Caffeine could act as an on-off switch for gene and cell therapies, giving doctors more precise control over powerful ...

Scientists at the Broad Institute and Mass General Brigham have built a generative AI model that creates short DNA segments ...

What if a cup of coffee could help treat cancer? Researchers at the Texas A&M Health Institute of Biosciences and Technology ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells. As a proof-of-concept, the ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive ...

What if you could flip a genetic switch to silence a gene, then turn it back on with a simple drug? For researchers, gene-switch tools offer that kind of control—and a new system called Cyclone may ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...