In a recent study published in the Journal of American Medical Association (JAMA) Oncology, researchers from California investigated the diagnostic outcomes of concurrent sequencing of ...

November 20, 2024 – Genome Research (https://genome.org) publishes a special issue highlighting advances in long-read sequencing applications in biology and medicine. In this first of two Special ...

Years of experiments and databases filled with RNA-seq results belie the simple reality that, until fairly recently, it was impossible to analyze RNA directly. The RNA-seq studies performed with ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

A full-size, high-density RNA microchip is about the size of a fingernail and can contain up to 780 000 unique RNA sequences, each occupying a ~14 x 14 μm² area. The presence and the quality of the ...

If you want to know what a cell, tissue, or organism is doing, molecularly speaking, you don’t look at its genome; you’ve got to look further downstream. One option: the transcriptome. One step beyond ...