The endoplasmic reticulum (ER) forms contacts with several organelles, and the most well-characterized of these are ER–mitochondria contacts. Regions of close contact between the ER and mitochondrial ...
The unfolded protein response (UPR) is a cytoprotective response that is aimed at restoring cellular homeostasis following physiological stress exerted on the endoplasmic reticulum (ER). The UPR is ...