Human cells usually contain two copies of most genes, one of which comes from the mother while the other comes from the father. It's long been thought that usually these two copies, or alleles of ...

Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding ...

A newly discovered genetic mutation unique to humans may help explain why we are significantly more vulnerable to cancer than our closest evolutionary relatives. Researchers at the University of ...

Flinders University researchers have discovered a rare genetic mutation that could explain why some people do not respond to ...

Scientists have created a complete map showing how hundreds of possible mutations in a key cancer gene influence tumor growth ...

Study results indicate that mutation strength may shape both tumor–immune system interactions and immunotherapy response.

New research from UC Davis Comprehensive Cancer Center has uncovered an evolutionary change that may explain why certain immune cells in humans are less effective at fighting solid tumors compared to ...

Huntington’s disease is a rare inherited neurological disorder that progressively affects movement, cognition and mental ...

The extinction of Neanderthals, our closest extinct human relatives, has long been a subject of intrigue and speculation. A groundbreaking study published in 2023 has shed new light on this mystery, ...

Genetic testing, including germline and somatic, is vital for prostate cancer prognosis and personalized treatment strategies. PARP inhibitors, targeting BRCA mutations, are a promising therapy for ...