BETHESDA, Md. (July 22, 2004) -- Microarray technology, sometimes referred to as biochips, has been extensively used to investigate genome-wide expression patterns and has facilitated a revolution in ...

For microarrays, the transition from research to clinical and diagnostic applications is well underway. Microarrays use a range of specific probes that are immobilized in known locations on a support ...

To test the hypothesis that the human genome project will uncover many genes not previously discovered by sequencing of expressed sequence tags (ESTs), we designed and produced a set of microarrays ...

Nature uses a common framework when building organisms as different as yeast, worms, fruit flies, mice, and humans. This makes it possible for scientists to learn about how our own genes work by ...

Microarrays are used to detect the expression of a diverse range of thousands of genes. They include microscopic slides that can be printed with a spot of a known sequence of DNA. This sequence then ...

While microarray technology is broadening its applications in genomics and proteomics, the technique remains a vibrant contributor in the area of gene expression. Much of the overall developmental ...

When it comes to enzymes, protein abundance does not necessarily translate into protein activity: Post-translational modifications such as phosphorylation can dramatically alter enzyme function.