Polygenic background bidirectionally modifies the penetrance of pathogenic variants in hypertrophic (HCM) and dilated (DCM) ...

New methods of analysis and novel markers are currently being identified to predict conditions with polygenic inheritance. These include polygenic risk scores (PRS), which are based on the presence of ...

Polygenic risk scores (PRS) combined with clinical factors improve POAG risk prediction, aiding in identifying high-risk patients. The study used OHTS data, showing low polygenic risk correlates with ...

There’s a new type of genetic testing known as polygenic embryo screening which promises to identify the risk of developing conditions like cancer, obesity and autism. But researchers are cautious.

Considerable progress has been made in uncovering common single nucleotide variants and developing mechanisms for genomic profiling. Using this knowledge routinely as part of clinical and public ...

Please provide your email address to receive an email when new articles are posted on . NEW ORLEANS — Causal artificial intelligence used to augment a polygenic risk score for CAD helped estimate how ...

Opinions differ as to the value of genetic information in the form of polygenic scores and the usefulness of polygenic score analysis as part of routine healthcare – clinical utility. Views on ...