Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...
Reducing RAD23A levels helped nerve cells better handle toxic TDP-43 protein clumps, improving survival and function in an ALS mouse model.
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...
Membrane proteins are vital for cellular signaling, transport, and communication, making them attractive drug targets despite their challenging properties. Advances in mass spectrometry have enabled ...
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Single protein is key to treating a deadly genetic heart disease targeting young athletes
A research team at the University of California San Diego has discovered a novel and promising method of treating arrhythmogenic cardiomyopathy (ACM), a rare inherited heart disease that can strike ...
Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...
Immunotherapy has transformed the field of cancer medicine. It has extended survival rates, reduced toxicity, and, in some cases, completely eradicated the tumor. Immunotherapy is a form of cancer ...
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at ...
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