Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 4 (January 25, 2022), pp. 1-11 (11 pages) RNA is a ubiquitous biomolecule that can serve as both catalyst ...

Charles Darwin described evolution as "descent with modification." Genetic information in the form of DNA sequences is copied and passed down from one generation to the next. But this process must ...

Now, a pair of Scripps Research Institute scientists has taken a significant step toward answering that question. The scientists have synthesized for the first time RNA enzymes that can replicate ...

UC Vice President for Research Patrick Limbach is a key figure in the National Academies’ massive undertaking to sequence RNA in the next 15 years. A chemist who leads the University of Cincinnati’s ...

The original version of this story appeared in Quanta Magazine. For a molecule of RNA, the world is a dangerous place. Unlike DNA, which can persist for millions of years in its remarkably stable, ...

In 2020, Juan Alfonzo, a professor of molecular biology, cell biology and biochemistry, began a project out of “pure COVID boredom.” Now, that project may become the largest scientific undertaking ...