From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body’s typically efficient DNA repair machinery and potentially affecting our health ...

Researchers suggest their approach has the potential to transform early disease detection and health monitoring across diverse clinical settings.

Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets for future precision medicine. Somatic genomics uncovers the outcomes of ...

Clinical Outcomes of Adult Patients With Newly Diagnosed Mixed Phenotype Acute Leukemia Colorectal tumors that underwent somatic next-generation sequencing (NGS) for 154-168 genes in an in-house ...

Fi Novelist Who Disappeared for Decades In “What We Are Seeking,” the cult author Cameron Reed returns to show us a strange, ...

Faculty in the Statistics in Genomics and Genetics Hub develop statistical and computational methods for analyzing high-throughput genomic and epigenomic data to advance biological discovery in cancer ...

Proteogenomics explores how genetic information translates into protein expression and function, and the role of changes across DNA, RNA, and proteins in influencing disease development and ...

Metformin effects on renal function in mCRPC during PSMA radiopharmaceutical therapy (RPT): A retrospective analysis. Clinical and demographic disparities in prostate cancer patients undergoing ...

Two new studies from Karolinska Institutet have investigated how mutations that occur in muscles and blood vessels over time can affect ageing. The studies, which are published in Nature Aging, show ...

Characteristics of Clonal Hematopoiesis (CH) Mutations - a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood ...