Circular RNA (circRNA) is a unique type of non-coding RNA produced by back splicing of mRNA to form the covalent junction without 3’-5’ polarity and poly(A) tail. CircRNA was first discovered about 30 ...

Researchers have gained new insights into largely overlooked circular RNAs in brain cells and the crucial role they play in diseases like Alzheimer’s and Parkinson’s. In addition to providing valuable ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

It’s no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers that can be used for diagnosis and better ways to selectively get medicine ...

Differentially expressed circFKBP8(5S,6) is a circular RNA with coding potential identified in control volunteers and patients with major depressive disorder (MDD). cFKBP8 is the protein encoded by ...

RNA therapeutics have been around since the late 1990s, but interest in these medicines has skyrocketed since the outbreak of the coronavirus pandemic and the success of messenger RNA (mRNA) vaccines.

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Obelisks—tiny RNA circles with protein-coding genes—have been found in the human microbiome, revealing a hidden RNA universe ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...