The cytoplasm of eukaryotic cells contains an elaborate filamentous protein meshwork — the cytoskeleton — which comprises three distinct but integrated fibrous polymers: filamentous actin (F-actin; ...

The cytoskeleton is a cellular scaffolding system whose functions include maintenance of cellular shape, enabling cellular migration, division, intracellular transport, signaling and membrane ...

SETD2, known for its involvement on gene expression, also can affect functions controlled by the cytoskeleton, such as movement, metastasis and migration, which are very important for cancer cells.

It forms networks of thin, flexible filaments that affect the shape, stiffness, and movement of cells. Studies have found that aging alters actin expression, disrupting the cytoskeleton’s functions, ...

Actin filaments (F-actin) are key components of sarcomeres, the basic contractile units of skeletal muscle myofibrils. A crucial step during myofibril differentiation is the sequential exchange of ...

In the 1950s, advances in microscopy techniques allowed scientists to visualize synaptic communication between two brain cells for the first time. 1,2 However, many details beyond the general synapse ...

A researcher has participated in a study describing what it is during the early stages of Alzheimer's that triggers the loss of dynamics and subsequent impairment of the dendritic spines, the ...

How did life leap from simple microbial cells to the complex, structured cells that make up animals, plants, and fungi? A new study in The EMBO Journal by researchers at the Indian Institute of ...

Prof. Michael Murrell's group (lead author Zachary Gao Sun, graduate student in physics) in collaboration with Prof. Garegin Papoian's group from the University of Maryland at College Park has found ...