Cytotoxic T lymphocytes play a crucial role in adaptive immunity, primarily defending against tumors and viruses. These cells develop within the thymus gland and undergo rapid activation upon ...

The Notch signaling pathway plays a pivotal role in determining cell fate, especially in the development and function of T cells. But mimicking this highly mechanical, contact-dependent pathway in the ...

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a ...

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration ...

F9 teratocarcinoma stem cells treated with retinoic acid (RA) and dibutyryl cAMP (but 2 cAMP) differentiate into embryonic parietal endoderm. Using heparin-affinity chromatography, endothelial cell ...

In their new study, the LJI scientists are the first to show that GPR25 is induced by a signaling molecule called TGF-β.