Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown ...

Osteoporosis is a common skeletal disorder characterized by excessive bone loss, leading to increased fragility and an ...

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases ...

Long recognized as the cell’s recycling depot, a new study has found lysosomes act as signaling hubs that coordinate metabolism and longevity by communicating signals across tissues. According to a ...

The team will investigate exactly how the enzyme drives lysosome function on a variety of fronts. Researchers will examine the enzyme's equilibrium and signaling and conduct a pathological ...

Hailong Zhang, Abdelrahim Zoued, Xu Liu, Brandon Sit, Matthew K. Waldor, Type I interferon remodels lysosome function and modifies intestinal epithelial defense, Proceedings of the National Academy of ...

An anticancer treatment technology that selectively targets cancer cell lysosomes and overcomes drug resistance has been developed by Professor Ja-Hyoung Ryu and his research team in the Department of ...