The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...

To recap, the transverse tubules are indispensable for efficient muscle function. Their key functions are: Rapidly transmit action potentials from the sarcolemma to the interior of the muscle fiber.

Using whole genome sequencing, researchers identified a single variant in a microRNA gene, MIR145-5p, as the source of multisystemic smooth muscle dysfunction syndrome, which had gone undiagnosed in a ...

Two related studies published today in Nature Metabolism show that a specialized intracellular recycling ...