The Arduino Nano uses a bootloader for handling programming the MCU, which requires the USB to serial bridge to be disconnected from anything that could interfere with the programming.

The Nano Every is a pin-equivalent substitute, so previous code and wiring will still work. Arduino has also swapped out the Nano's mini-USB connector in favor of micro-USB.

Learn what a USB to Serial adapter is used for, when you might need one, and whether installing a driver is required for it to work properly.

Windows Update drivers bricking USB serial chips beloved of hardware hackers The move to combat counterfeit chips leaves hobbyists stuck in the middle.