In the manufacture of solid dosage forms, the rate at which the active pharmaceutical ingredient (API) is dissolved into solvents simulating the digestive tract fluids is determined with dissolution ...

an active pharmaceutical ingredient is the active ingredient contained in a drug and it is the basic material with the desired pharmaceutical properties. Active pharmaceutical ingredients play core ...

Advances in dissolution testing equipment are helping to meet user demands to a certain degree; however, more innovation in the space may be necessary for novel therapies, such as biologics.

The dissolution profile of inhaled drugs underpins therapeutic efficacy and is an area of increasing regulatory scrutiny, particularly for the demonstration of bioequivalence in a generic. The new ...

In addition to use of dissolution testers, this three-day course will also cover equipment qualification, development and validation of dissolution procedures, and the use of dissolution testing in ...

This paper discusses what causes cross-linking, how cross-linking is addressed with addition of enzymes, and consideration for occasional high results that can be obtained during release testing. A ...

Mark Hammond, Business Development Manager of Melbourn Scientific has explained that a large number of the more recent active ingredients are poorly soluble in traditional media and expose the ...