Frontiers

Switching from febuxostat to dotinurad, a novel selective urate reabsorption inhibitor, may substantially reduce serum urate levels, through URAT1 inhibition, potentially ...

Background: Dotinurad is a novel selective urate transporter 1 (URAT1) inhibitor recently introduced in Japan. This study aims to evaluate the efficacy and safety of dotinurad in hyperuricemic ...
Frontiers

Multimodal prehabilitation is an effective strategy to reduce postoperative complications and improve physical function and anxiety in patients with colorectal cancer ...

Background: Preoperative prehabilitation represents a viable approach to improve postoperative recovery and quality of life in colorectal cancer (CRC) patients, though debates persist regarding the ...